Welcome to the Amyloidogenic Sequence Knowledge Base (ASKB) server. This server calculates contact-dependent secondary structure propensites (CSSP) of a given amino acid sequence for diverse tertiary contact states. First users should read introductory page first.

Reference

1. Detecting hidden sequence propensity for amyloid fibril formation, S. Yoon and W. J. Welsh, Protein Science 13, 2149-60 (2004).

2. Rapid Assessment of Contact-Dependent Secondary Structure Propensity: Relevance to Amyloidogenic Sequences, S. Yoon and W. J. Welsh, Proteins: Structure, Function, and Bioinformatics 60, 110-17 (2005).

Protein sequence single letter code or FASTA format Protein name Sample query sequences